The Manhattan Principles
History of Medicine / Public Health

The Manhattan Principles

From the CDC Webpage on the twelve Manhattan Principles: These “Manhattan Principles” urge world leaders, civil society, the global health community, and institutions of science to holistically approach the prevention of epidemic/epizootic disease and the maintenance of ecosystem integrity by: Recognizing the link between human, domestic animal, and wildlife health, and the threat disease poses … Continue reading

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Comparing the Rotavirus Vaccines in India
Infectious Diseases / Public Health

Comparing the Rotavirus Vaccines in India

Comparisons of different rotavirus vaccines are difficult to make with a lot of precision because of the differing populations, protocols, attack rates, and study procedures which have been employed to assess the efficacy of the vaccines. Given the rather recent deployment of the vaccines, there are very limited evidence on their effectiveness in the population/community-setting. … Continue reading

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Debunking EBM / Public Health

BGR-34 for Diabetes: Where is the evidence?

An herbal drug, developed jointly by the National Botanical Research Institute (NBRI) and the Central Institute of Medicinal and Aromatic Plants (CIMAP), branded as BGR-34, has been commercialized by Delhi-based Aimil Pharmaceuticals and marketed as a potentially side-effect free treatment for diabetes. However, a search for publications outlining trials conducted to support the claimed “67% … Continue reading

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Infectious Diseases / Public Health

Turning to the “Infected Jelly” to Treat Ebola

The NEJM has come out with a very interesting paper: Evaluation of Convalescent Plasma for Ebola Virus Disease in Guinea. The explosive outbreak of Ebola Virus Disease in West Africa last year had hijacked the headlines and media space in a big way. Multiple solutions were touted, including the vaccine trial STRIVE. Few articles, however, looked … Continue reading

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Infectious Diseases / Public Health

If Carbapenems Go, Can Colistin be Far Behind?

I wrote about the disaster-in-the-making discovery of transmissible resistance to colistin, a last resort antibiotic, when the Lancet Infectious Diseases published a paper based on data coming out from surveillance in China. At that point of time, the isolation of the transmissible gene providing resistance (mcr1 gene) gained a lot of attention. Maryn McKenna’s blog post went … Continue reading

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Towards Universal Health Coverage: The Lancet Commission and Some Personal Thoughts
Medcetera / Public Health

Towards Universal Health Coverage: The Lancet Commission and Some Personal Thoughts

The Lancet Commission on Investing in Health (CIH) has come up with an ambitious framework (1) and an editorial comment accompanying it (2) in the recent issue of the journal. The Editorial makes a strong pitch for a systematic adoption of pro-poor strategies to bolster the adoption of UHC. In this commentary authored by the … Continue reading

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