This study has been popping up all over the AMR radar for me for the past week; so, when I was stuck in traffic today, I decided to sit down and give the article a read. An interesting read, which does provide insights into the rapid global spread of AMR, this article, however, has been taken way out of context by the headlines of tabloids … Continue reading AMR Goes Global: Detection of Allochthonous Anthropogenic AMR Genes in High Arctic Regions
My thoughts on a recently published study that looks at the Continue reading Study from Private Hospital Chain Reveals High Mortality in Patients with Multi Drug Resistant Infections
I wrote about the disaster-in-the-making discovery of transmissible resistance to colistin, a last resort antibiotic, when the Lancet Infectious Diseases published a paper based on data coming out from surveillance in China. At that point of time, the isolation of the transmissible gene providing resistance (mcr1 gene) gained a lot of attention. Maryn McKenna’s blog post went viral and there was a lot of tornadoes in Twitter. … Continue reading If Carbapenems Go, Can Colistin be Far Behind?
Polymyxins are a group of bacterial origin cyclic polypeptides with antibacterial properties. It was isolated by a Japanese researcher in 1949 from a jar of fermenting bacteria. Colistin, also known as Polymyxin E, which is produced by the bacteria Paenibacillus polymyxa var. colistinus, is a polypeptide antibiotic, which is effective against almost all gram-negative bacilli. Owing to its nephrotoxocity and the subsequent development of more targeted and safe antibiotics, colistin … Continue reading The Apocalypse is HERE: Transmissible Resistance to Last Resort Antibiotic (Colistin)