Welcome to the second week of research round up, where I look back on some of the interesting research papers I happened to read this week. Notice a pattern yet? Yeah… I am working on a lot of antimicrobial resistance related stuff! 1. Series on Antimicrobial Resistance in The Lancet: The series on the rising … Continue reading
The prescient words of Alexander Fleming, who was awarded the Nobel Prize in Medicine or Physiology in 1945 for his seredipitous discovery of the antibiotic, Penicillin, are worth a mention when it comes to discussing the wise aphorisms around antimicrobial resistance. In an interview given to The New York Times in 1945, he notes that: … Continue reading
I am working on a document outlining strategies for monitoring and surveillance of antimicrobial resistance (hence the recent plethora of posts on the topic!) and sometimes, these documents spout some beautifully poetic paragraphs amidst pages and pages of policy jargon! So I thought of blogging them as and when I come across them! From Shaban … Continue reading
I wrote about the disaster-in-the-making discovery of transmissible resistance to colistin, a last resort antibiotic, when the Lancet Infectious Diseases published a paper based on data coming out from surveillance in China. At that point of time, the isolation of the transmissible gene providing resistance (mcr1 gene) gained a lot of attention. Maryn McKenna’s blog post went … Continue reading
Polymyxins are a group of bacterial origin cyclic polypeptides with antibacterial properties. It was isolated by a Japanese researcher in 1949 from a jar of fermenting bacteria. Colistin, also known as Polymyxin E, which is produced by the bacteria Paenibacillus polymyxa var. colistinus, is a polypeptide antibiotic, which is effective against almost all gram-negative bacilli. Owing to its nephrotoxocity and … Continue reading
The Journal of Global Antimicrobial Resistance has published an interesting review article discussing the impact of scale up of drug donations to control neglected helminthiasis in the developing countries through aid-assisted preventive chemotherapy of vulnerable populations. The highlights of the article include: Scale-up in drug donations for control of Neglected Tropical Diseases subject to Preventive … Continue reading
According to a study published in The Lancet Infectious Diseases, the dangerous, artemisinin-resistant malaria is clawing at the borders of India and Myanmar. Go to article From the article abstract: Summary Background Emergence of artemisinin resistance in southeast Asia poses a serious threat to the global control of Plasmodium falciparum malaria. Discovery of the K13 marker has … Continue reading
