Aphorisms #2: Antimicrobial Resistance
Infectious Diseases / Medcetera

Aphorisms #2: Antimicrobial Resistance

The prescient words of Alexander Fleming, who was awarded the Nobel Prize in Medicine or Physiology in 1945 for his seredipitous discovery of the antibiotic, Penicillin, are worth a mention when it comes to discussing the wise aphorisms around antimicrobial resistance. In an interview given to The New York Times in 1945, he notes that: … Continue reading

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Infectious Diseases / Medcetera

Aphorisms #1: Antimicrobial Resistance

I am working on a document outlining strategies for monitoring and surveillance of antimicrobial resistance (hence the recent plethora of posts on the topic!) and sometimes, these documents spout some beautifully poetic paragraphs amidst pages and pages of policy jargon! So I thought of blogging them as and when I come across them! From  Shaban … Continue reading

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Infectious Diseases / Public Health

If Carbapenems Go, Can Colistin be Far Behind?

I wrote about the disaster-in-the-making discovery of transmissible resistance to colistin, a last resort antibiotic, when the Lancet Infectious Diseases published a paper based on data coming out from surveillance in China. At that point of time, the isolation of the transmissible gene providing resistance (mcr1 gene) gained a lot of attention. Maryn McKenna’s blog post went … Continue reading

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The Apocalypse is HERE: Transmissible Resistance to Last Resort Antibiotic (Colistin)
Infectious Diseases / Medcetera / Public Health

The Apocalypse is HERE: Transmissible Resistance to Last Resort Antibiotic (Colistin)

Polymyxins are a group of bacterial origin cyclic polypeptides with antibacterial properties. It was isolated by a Japanese researcher in 1949 from a jar of fermenting bacteria. Colistin, also known as Polymyxin E, which is produced by the bacteria Paenibacillus polymyxa var. colistinus, is a polypeptide antibiotic, which is effective against almost all gram-negative bacilli. Owing to its nephrotoxocity and … Continue reading

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Anthelminthic Drug Donation in the Epoch of Drug Resistance
Infectious Diseases

Anthelminthic Drug Donation in the Epoch of Drug Resistance

The Journal of Global Antimicrobial Resistance has published an interesting review article discussing the impact of scale up of drug donations to control neglected helminthiasis in the developing countries through aid-assisted preventive chemotherapy of vulnerable populations. The highlights of the article include: Scale-up in drug donations for control of Neglected Tropical Diseases subject to Preventive … Continue reading

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Infectious Diseases / Outbreak Watch

Artemisinin-Resistant Malaria Threatens India

According to a study published in The Lancet Infectious Diseases, the dangerous, artemisinin-resistant malaria is clawing at the borders of India and Myanmar. Go to article From the article abstract: Summary Background Emergence of artemisinin resistance in southeast Asia poses a serious threat to the global control of Plasmodium falciparum malaria. Discovery of the K13 marker has … Continue reading

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