AMR Goes Global: Detection of Allochthonous Anthropogenic AMR Genes in High Arctic Regions

This study has been popping up all over the AMR radar for me for the past week; so, when I was stuck in traffic today, I decided to sit down and give the article a read. An interesting read, which does provide insights into the rapid global spread of AMR, this article, however, has been taken way out of context by the headlines of tabloids … Continue reading AMR Goes Global: Detection of Allochthonous Anthropogenic AMR Genes in High Arctic Regions

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Study from Private Hospital Chain Reveals High Mortality in Patients with Multi Drug Resistant Infections

My thoughts on a recently published study that looks at the Continue reading Study from Private Hospital Chain Reveals High Mortality in Patients with Multi Drug Resistant Infections

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If Carbapenems Go, Can Colistin be Far Behind?

I wrote about the disaster-in-the-making discovery of transmissible resistance to colistin, a last resort antibiotic, when the Lancet Infectious Diseases published a paper based on data coming out from surveillance in China. At that point of time, the isolation of the transmissible gene providing resistance (mcr1 gene) gained a lot of attention. Maryn McKenna’s blog post went viral and there was a lot of tornadoes in Twitter. … Continue reading If Carbapenems Go, Can Colistin be Far Behind?

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The Apocalypse is HERE: Transmissible Resistance to Last Resort Antibiotic (Colistin)

Polymyxins are a group of bacterial origin cyclic polypeptides with antibacterial properties. It was isolated by a Japanese researcher in 1949 from a jar of fermenting bacteria. Colistin, also known as Polymyxin E, which is produced by the bacteria Paenibacillus polymyxa var. colistinus, is a polypeptide antibiotic, which is effective against almost all gram-negative bacilli. Owing to its nephrotoxocity and the subsequent development of more targeted and safe antibiotics, colistin … Continue reading The Apocalypse is HERE: Transmissible Resistance to Last Resort Antibiotic (Colistin)

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Anthelminthic Drug Donation in the Epoch of Drug Resistance

The Journal of Global Antimicrobial Resistance has published an interesting review article discussing the impact of scale up of drug donations to control neglected helminthiasis in the developing countries through aid-assisted preventive chemotherapy of vulnerable populations. The highlights of the article include: Scale-up in drug donations for control of Neglected Tropical Diseases subject to Preventive Chemotherapy calls for monitoring drug efficacy. Monitoring efficacy of anthelmintics … Continue reading Anthelminthic Drug Donation in the Epoch of Drug Resistance

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Artemisinin-Resistant Malaria Threatens India

According to a study published in The Lancet Infectious Diseases, the dangerous, artemisinin-resistant malaria is clawing at the borders of India and Myanmar. Go to article From the article abstract: Summary Background Emergence of artemisinin resistance in southeast Asia poses a serious threat to the global control of Plasmodium falciparum malaria. Discovery of the K13 marker has transformed approaches to the monitoring of artemisinin resistance, allowing introduction … Continue reading Artemisinin-Resistant Malaria Threatens India

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Fatal Nosocomial Infection with Extensively Resistant, Hypervirulent Acinetobacter

Acinetobacter baumanii is a typical critical care “pest” in that it causes infections with high degrees of morbidity and mortality in severely ill patients, especially those who are immunosuppressed. However, a recent publication has brought to view the fact that a clade B strain of Acinetobacter baumanii was associated with six deaths in a hospital setting. This new clade B strain is notable because it is extensively … Continue reading Fatal Nosocomial Infection with Extensively Resistant, Hypervirulent Acinetobacter

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