Convalescent Plasma in COVID-19: The Dutch ConCOVID Randomized Controlled Trial Halted for Re-design

The Dutch CONCOVID Trial intended to look at the effect of convalescent plasma therapy on mortality in COVID-19 patients. It has recently been halted after recruiting only about a fifth of its calculated sample size after some very unexpected results were observed. These are my quick thoughts on the matter!

Cochrane Students’ Journal Club: An Introduction

Why this Journal Club? Three simple reasons.. To provide students with an opportunity to critically read literature outside their key area of study: To provide students with an opportunity to critically discuss scientific papers. To sensitize them to EBM. Okay. So this is how it goes... A clinical scenario asking a question on the potential … Continue reading Cochrane Students’ Journal Club: An Introduction

Rifaximin in IBS: A Quick Fix?

This study published in the NEJM seems to have tackled the really dicey issue of unearthing a pharmacotherapeutic agent to deal with the rather ubiquitous, though poorly understood, and more often than not, even less poorly managed problem of irritable bowel syndrome. The irritable bowel syndrome (IBS) is a functional gastrointestinal disorder characterized by recurring … Continue reading Rifaximin in IBS: A Quick Fix?